语言模型既展示了定量的改进，又展示了新的定性功能，随着规模的增加。尽管它们具有潜在的变革性影响，但这些新能力的特征却很差。为了为未来的研究提供信息，为破坏性的新模型能力做准备，并改善社会有害的效果，至关重要的是，我们必须了解目前和近乎未来的能力和语言模型的局限性。为了应对这一挑战，我们介绍了超越模仿游戏基准（Big Bench）。 Big Bench目前由204个任务组成，由132家机构的442位作者贡献。任务主题是多样的，从语言学，儿童发展，数学，常识性推理，生物学，物理学，社会偏见，软件开发等等。 Big-Bench专注于被认为超出当前语言模型的功能的任务。我们评估了OpenAI的GPT型号，Google内部密集变压器体系结构和大型基础上的开关稀疏变压器的行为，跨越了数百万到数十亿个参数。此外，一个人类专家评估者团队执行了所有任务，以提供强大的基准。研究结果包括：模型性能和校准都随规模改善，但绝对的术语（以及与评估者的性能相比）；在模型类中的性能非常相似，尽管带有稀疏性。逐渐和预测的任务通常涉及大量知识或记忆成分，而在临界规模上表现出“突破性”行为的任务通常涉及多个步骤或组成部分或脆性指标；社交偏见通常会随着含糊不清的环境而随着规模而增加，但这可以通过提示来改善。

目的：慢性主动脉疾病的监测成像，如解剖，依赖于在预定义主动脉地标随时间获得和比较预定义主动脉标志的横截面直径测量。由于缺乏鲁棒工具，横截面平面的方向由高训练的操作员手动定义。我们展示了如何有效地使用诊所中常规收集的手动注释来缓解该任务，尽管在测量中存在不可忽略的互操作器可变性。影响：通过利用不完美，回顾性的临床注释，可以缓解或自动化且重复的成像任务的弊端。方法论：在这项工作中，我们结合了卷积神经网络和不确定量化方法来预测这种横截面的取向。我们使用11个操作员随机处理的临床数据进行培训，并在3个独立运营商处理的较小集合上进行测试，以评估互通器变异性。结果：我们的分析表明，手动选择的横截面平面的特点是10.6 ^ \ CirC $ 10.6 ^ \ riC $和每角度为21.4美元的协议限额为95％我们的方法显示，静态误差减少3.57秒^ \ rIC $（$ 40.2 $％）和$ 4.11 ^ \ rIC $（$ 32.8 $％），而不是5.4 ^ \ rIC $（$ 49.0 $％）和16.0美元^ \ CIRC $（$ 74.6 $％）对手动处理。结论：这表明预先存在的注释可以是诊所的廉价资源，以便于易于提出和重复的任务，如横截面提取，以便监测主动脉夹层。

Recent advances in artificial intelligence (AI) have significantly intensified research in the geoscience and remote sensing (RS) field. AI algorithms, especially deep learning-based ones, have been developed and applied widely to RS data analysis. The successful application of AI covers almost all aspects of Earth observation (EO) missions, from low-level vision tasks like super-resolution, denoising, and inpainting, to high-level vision tasks like scene classification, object detection, and semantic segmentation. While AI techniques enable researchers to observe and understand the Earth more accurately, the vulnerability and uncertainty of AI models deserve further attention, considering that many geoscience and RS tasks are highly safety-critical. This paper reviews the current development of AI security in the geoscience and RS field, covering the following five important aspects: adversarial attack, backdoor attack, federated learning, uncertainty, and explainability. Moreover, the potential opportunities and trends are discussed to provide insights for future research. To the best of the authors' knowledge, this paper is the first attempt to provide a systematic review of AI security-related research in the geoscience and RS community. Available code and datasets are also listed in the paper to move this vibrant field of research forward.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

The lack of standardization is a prominent issue in magnetic resonance (MR) imaging. This often causes undesired contrast variations due to differences in hardware and acquisition parameters. In recent years, MR harmonization using image synthesis with disentanglement has been proposed to compensate for the undesired contrast variations. Despite the success of existing methods, we argue that three major improvements can be made. First, most existing methods are built upon the assumption that multi-contrast MR images of the same subject share the same anatomy. This assumption is questionable since different MR contrasts are specialized to highlight different anatomical features. Second, these methods often require a fixed set of MR contrasts for training (e.g., both Tw-weighted and T2-weighted images must be available), which limits their applicability. Third, existing methods generally are sensitive to imaging artifacts. In this paper, we present a novel approach, Harmonization with Attention-based Contrast, Anatomy, and Artifact Awareness (HACA3), to address these three issues. We first propose an anatomy fusion module that enables HACA3 to respect the anatomical differences between MR contrasts. HACA3 is also robust to imaging artifacts and can be trained and applied to any set of MR contrasts. Experiments show that HACA3 achieves state-of-the-art performance under multiple image quality metrics. We also demonstrate the applicability of HACA3 on downstream tasks with diverse MR datasets acquired from 21 sites with different field strengths, scanner platforms, and acquisition protocols.

Large language models (LLMs) have been shown to be able to perform new tasks based on a few demonstrations or natural language instructions. While these capabilities have led to widespread adoption, most LLMs are developed by resource-rich organizations and are frequently kept from the public. As a step towards democratizing this powerful technology, we present BLOOM, a 176B-parameter open-access language model designed and built thanks to a collaboration of hundreds of researchers. BLOOM is a decoder-only Transformer language model that was trained on the ROOTS corpus, a dataset comprising hundreds of sources in 46 natural and 13 programming languages (59 in total). We find that BLOOM achieves competitive performance on a wide variety of benchmarks, with stronger results after undergoing multitask prompted finetuning. To facilitate future research and applications using LLMs, we publicly release our models and code under the Responsible AI License.

Artificial Intelligence (AI) is having a tremendous impact across most areas of science. Applications of AI in healthcare have the potential to improve our ability to detect, diagnose, prognose, and intervene on human disease. For AI models to be used clinically, they need to be made safe, reproducible and robust, and the underlying software framework must be aware of the particularities (e.g. geometry, physiology, physics) of medical data being processed. This work introduces MONAI, a freely available, community-supported, and consortium-led PyTorch-based framework for deep learning in healthcare. MONAI extends PyTorch to support medical data, with a particular focus on imaging, and provide purpose-specific AI model architectures, transformations and utilities that streamline the development and deployment of medical AI models. MONAI follows best practices for software-development, providing an easy-to-use, robust, well-documented, and well-tested software framework. MONAI preserves the simple, additive, and compositional approach of its underlying PyTorch libraries. MONAI is being used by and receiving contributions from research, clinical and industrial teams from around the world, who are pursuing applications spanning nearly every aspect of healthcare.

我们提供了证据表明，学到的密度功能理论（``dft'）的力场已准备好进行基态催化剂发现。我们的关键发现是，尽管预测的力与地面真相有很大差异，但使用从超过50 \％的评估系统中使用RPBE功能的能量与使用RPBE功能相似或较低能量的力量的力量与使用RPBE功能相似或较低的力量放松。这具有令人惊讶的含义，即学习的潜力可能已经准备好在挑战性的催化系统中替换DFT，例如在Open Catalyst 2020数据集中发现的电位。此外，我们表明，在局部谐波能量表面上具有与目标DFT能量相同的局部谐波能量表面训练的力场也能够在50 \％的情况下找到较低或相似的能量结构。与在真实能量和力量训练的标准模型相比，这种``简易电位''的收敛步骤更少，这进一步加速了计算。它的成功说明了一个关键：即使模型具有高力误差，学到的电位也可以定位能量最小值。结构优化的主要要求仅仅是学到的电位具有正确的最小值。由于学到的电位与系统大小的速度快速且尺寸为线性，因此我们的结果开辟了快速找到大型系统基础状态的可能性。

流行模型是理解传染病的强大工具。但是，随着它们的大小和复杂性的增加，它们可以迅速在计算上棘手。建模方法的最新进展表明，替代模型可用于模拟具有高维参数空间的复杂流行模型。我们表明，深层序列到序列（SEQ2SEQ）模型可以作为具有基于序列模型参数的复杂流行病模型的准确替代物，从而有效地复制了季节性和长期传播动力学。一旦受过培训，我们的代理人可以预测场景比原始模型快几千倍，从而使其非常适合策略探索。我们证明，用博学的模拟器代替传统的流行模型有助于强大的贝叶斯推断。

我们通过策略提取（MSVIPER）提出了多种可验证的增强学习，这是一种策略蒸馏到决策树以改进机器人导航的新方法。 MSVIPER使用任何强化学习（RL）技术来学习一项“专家”政策，涉及学习国家行动映射，然后使用模仿学习来从中学习决策树策略。我们证明，MSVIPER会导致有效的决策树，并可以准确模仿专家政策的行为。此外，我们提出了有效的政策蒸馏和树修改技术，这些技术利用决策树结构，可以改进政策而无需再培训。我们使用我们的方法来改善用于室内和室外场景的基于RL的机器人导航算法的性能。我们证明了在减少冻结和振荡行为（减少95 \％降低）方面的好处。